No I have not seen it. Is there somewhere I would be able to catch it online? Also, it is a bit disappointing that the creator did not get it right the first time. I like for the man behind the scenes to have his own vision which is not too influenced by the corporate TV market. I still love the show though obviously.
It's rare that tv shows don't end up different from pilots. That's what they are for a tester to see what works and what doesn't. Don't confuse first episodes with pillots. I remember Buffy had a dodgy pilot with a very different Willow and changed for the better.
As for the pilot itself. Penny was complete trash, they've actually taken her back towards that character unfortunately. Sheldon was far less socially naive and there was another character I can't remember the name of who had a crush on Leonard. I think Leonard was pretty similar.