Since we are on this subject, the biggest error I saw in all the show was in Season 1 Episode 2 when Penny goes in Leonard's apartment to get angry at them.
When Penny says to Sheldon : "What kind of doctor removes shoes from asses?", she looks at him directly with her arms down in one frame, with 1 hand on the hip in another she has her 2 hands on her hips, all of this in a 3-4 seconds interval. Feels really akward.
But it's a REALLY SMALL dent on a perfect show. Can't wait for November 2nd.